THE MOST NOVEL VACCINES

Nucleic acid vaccines
Nucleic acid vaccines are made up of mRNA or plasmid DNA encoding viral antigenic components to express specific proteins of a pathogen after injection. The technology of mRNA vaccines made its breakthrough with SARS-CoV-2. With dozens of new applications including HIV, cancer, shingles, flu, cardiovascular applications, or Zika, it is a very promising technology.

➕ Multiple advantages such as exceptionally fast modifiability in response to mutations, high versatility, high safety, and a fast, cost-efficient, and scalable production in a cell-free system. Vaccines for multiple indications can be produced using the same process.

➖ During vaccination the mRNA must be delivered directly into cells, which requires specific injection devices, electroporation, or a carrier molecule. mRNA vaccines exhibit instability and require a cold chain